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Jantine Broek

Computational and AI/ML Scientist

Publications

Do place cells dream of deceptive moves in a signaling game?

Fenton AA, Hurtado JR, Broek JAC, Park EH, Mishra B (2024). Neuroscience.

Application of the PHENotype SIMulator for rapid identification of potential candidates in effective COVID-19 drug repurposing

Maria NI, Rapicavoli RV, Alaimo S, Bischof E, Stasuzzo A, Broek JAC, et al. (2023). Heliyon 9 (3).

Diagnostic model development for schizophrenia based on peripheral blood mononuclear cell subtype-specific expression of metabolic markers

Zaki JK, Lago SG, Rustogi N, Gangadin SS, Benacek J, Van Rees GF, Broek JAC, et al. (2022). Translational Psychiatry 12 (1), 457.

Rapid identification of druggable targets and the power of the phenotype simulator for effective drug repurposing in COVID-19

Maria NI, Rapicavoli RV, Alaimo S, Bischof E, Stasuzzo A, Broek JAC, et al. (2021). Research Square.

Exploring cellular markers of metabolic syndrome in peripheral blood mononuclear cells across the neuropsychiatric spectrum

Lago SG, Tomasik J, Van Rees GF, Rubey M, Gonzalez-Vioque E, Broek JAC, et al. (2021). Brain, Behavior, and Immunity 91, 673-682.

Generalisation of neuronal excitability allows for the identification of an excitability change parameter that links to an experimentally measurable value.

Broek JAC, Drion G (2020). arXiv:2011.00297v1, Quantitative Biology.

Anergy to Synergy - The Energy Fueling the RxCOVEA Framework.

Bischof E, Broek JAC, Cantor C, Duits A, Maria N, Mishra B, Rudolph L, et. al (2020). International Journal for Multiscale Computational Engineering.

Exploring cellular markers of metabolic syndrome in peripheral blood mononuclear cells across the neuropsychiatric spectrum.

Lago S, Tomasik J, van Rees G, Fuetterer M, Gonzalez Vioque E, Ramsey J, Haenisch F, Broek JAC, Vázquez-Bourgon J, Papiol S, Suárez-Pinilla P, Ruland T, Auyeung B, Demireva O, Kabacs N, Arolt V, Baron-Cohen S, Crespo-Facorro B, Bahn S (2020). Brain Behavior and Immunity.

Effect of different inhibitory cells on state changes in stabilized supralinear network models.

Broek JAC, Ahmadian Y, McCormick DA (2018). manuscript in preparation.

Kv1.1-modulated alterations in neuronal excitability and short-term synaptic plasticity in the prefrontal cortex of a mouse model of mental illness.

Crabtree GW, Sun Z, Kvajo M, Broek JAC, Fenelon K, McKellar H, Xiao L, Bahn S, O'Donnell J, MacDermott AB, Gogos JA (2017). Journal of Neuroscience, 37.15: 4158-4180.

Cell Type-Specific Effects of Mutant DISC1: A Proteomics Study.

Xia, M., Broek, JAC, Jouroukhin, Y., Schoenfelder, J., Abazyan, S., Jaaro-Peled, H., & Pletnikov, M. (2016). Molecular neuropsychiatry, 2(1), 28-36.

Peripheral characterization in Asperger syndrome includes sex-specific changes at both transcriptomic and proteomic level.

Broek JA, Ramsey JM, Auyeung B, Baron-Cohen S, Bahn S (2015). Molecular neuropsychiatry, 2(1), 28-36.

Synaptic vesicle dynamic changes in a model of fragile X.

Broek JAC, Van 't Spijker H, Ozcan S, De Gruiter HM, Haasdijk ED, Willemsen R, De Zeeuw CI, Bahn S (2016). Mol Autism 7(1):11.

Munc18-1 redistributes in nerve terminals in an activity- and PKC-dependent manner.

Cijsouw T, Weber JP, Broeke JH, Broek JAC, Schut D, Kroon T, Saarloos I, Verhage M, Toonen RF. (2015). J Cell Biol 204(5): 759-75.

Proteomic analysis of post mortem brain tissue from autism patients: evidence for opposite changes in prefrontal cortex and cerebellum in synaptic connectivity-related proteins.

Broek JAC, Guest PC, Rahmoune H, Bahn S. (2014). Mol Autism 5: 41.

Identification of an age-dependent biomarker signature in children and adolescents with autism spectrum disorders.

Ramsey JM, Guest PC, Broek JAC, Glennon JC, Rommelse N, Franke B, Rahmoune H, Buitelaar JK, Bahn S. (2013). Mol Autism 4(1):27.

The need for a comprehensive molecular characterization of autism spectrum disorders.

Broek JAC, Brombacher E, Stelzhammer V, Guest PC, Rahmoune H, Bahn S. (2014). Int J Neuropsychopharmacol: 1-23